Rigor and Reproducibility One Year Later: How Has the Biomedical Community Responded? A Workshop at the 2017 AAAS Meeting

Rigor and Reproducibility One Year Later: How Has the Biomedical Community Responded? A Workshop at the 2017 AAAS Meeting

This is a guest post by Future of Research policy activist, Adriana Bankston.     The AAAS meeting is a useful platform in which to discuss many important issues plaguing science today. Fundamental to the integrity of the scientific enterprise is being able to perform rigorous experiments at the bench, and successfully reproducing research findings. To this end, the National Institutes of Health’s (NIH) has implemented Rigor and Reproducibility guidelines, which represent fundamental changes to the grant application and review process. These guidelines went into effect on January 25, 2016. A session at the 2017 AAAS meeting entitled “Rigor and Reproducibility One Year Later: How Has the Biomedical Community Responded?” explored the feedback received from both the NIH and the research community following these guidelines, and discussed how to best implement them to achieve both increased rates of reproducibility and dramatic returns on research funding investments.   The session was moderated by Leonard Freedman from Global Biological Standards Institute (GBSI), a non-profit organization dedicated to enhancing the credibility, reproducibility, and translatability of biomedical research through best practices and standards. One of their initiatives, Reproducibility2020, aims to significantly improve the quality of preclinical biological research by the year 2020. The session featured Michael Lauer from the National Institutes of Health and William Kaelin from the Howard Hughes Medical Institute as speakers, and Judith Kimble from the University of Wisconsin, Madison, also a member of the steering committee for Rescuing Biomedical Research, as the discussant.   Michael Lauer on p-hacking and cognitive biases Michael Lauer began his talk by discussing the John Ioannidis paper from 2005 entitled “Why Most Published Research...